The authorities in Mali have confirmed the death of the country's first Ebola patient, a two-year-old girl.
The girl's mother died in Guinea a few weeks ago and the child was then brought by relatives to Mali.
The World Health Organisation said the toddler had travelled hundreds of kilometres by bus from Guinea through Mali showing symptoms of the disease.
More than 40 people known to have come into contact with her have been quarantined.
The girl was being treated in the western town of Kayes, after arriving at a hospital on Wednesday.
"The child's symptomatic state during the bus journey is especially concerning, as it presented multiple opportunities for exposures, including high-risk exposures, involving many people," the WHO said.
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